Ranbaxy ‘Sold Adulterated Drugs Liptor’, Admits


Ranbaxy, the international Drug Manufacturer admitted in the United States to charges of making and distributing adulterated drugs at its two Indian plants of Paonta Sahib and Dewas and agreed to a $500 million settlement.

Ranbaxy Laboratories, India

Ranbaxy .

Daiichi Sankyo believes certain former shareholders of Ranbaxy concealed and misrepresented critical information concerning the US Department of Justice and Food and Drug Administration (FDA) investigations,” Daiichi said in a statement.

FDA warning to Ranbaxy.

Drug Adulteration.

Adulterated Drugs.

Mr. Malvinder Mohan Singh
CEO & Managing Director
Ranbaxy Laboratories Limited
Corporate Office
Plot 90; Sector 32
Gurgaon – 122001 (Haryana)
India
Dear Mr. Singh:
The Center for Drug Evaluation and Research has determined that Ranbaxy Laboratories
Limited (Ranbaxy) submitted untrue statements of material fact in abbreviated and new
drug applications filed with the Agency. These findings concern the submission of
information, such as from stability test results in support of pending and approved drug
applications, from the Ranbaxy Laboratories Limited site located at Paonta Sahib,
Sirmour District, Himachal Pradesh, India, (herein referred to as the “Paonta Sahib site”).
The following are examples of the observations that support our conclusion that Ranbaxy
submitted untrue statements of material fact in drug applications filed with the Agency:
1. Ranbaxy submitted stability information in numerous approved and pending
applications that contain untrue statements of material fact, because Ranbaxy failed to
include critical information about the storage and testing of the product. During a
February 2006 inspection of the Paonta Sahib manufacturing facility, FDA found
that hundreds of stability samples, many of which were being used for room
temperature or accelerated stability studies, were being stored in refrigerators at
approximately between the time they were removed from their stability
chamber and the time they were tested. Among other things, FDA investigators
found that the sample logbooks did not identify the samples that were being held in
the refrigerators, their storage duration in the refrigerators, and the justification for
this storage. FDA issued a June 15, 2006 warning letter to Ranbaxy based on its
findings during this inspection, including the circumstances of these refrigerated
stability samples.
2. Ranbaxy submitted an August 26, 2006 warning letter response that included
corrections to the stability data previously submitted to the agency in several
abbreviated new drug applications (ANDAs). The corrected stability test reports for
Fluconazole Tablets, Ciprofloxacin Tablets, and show instances
where stability test dates that previously had been submitted to the applications were
false. In some cases stability testing was conducted several months later than the
dates reported in the applications. Additionally, the firm reported stability test results
for a given batch as occurring at the required accelerated or long term (e.g., 3, 6, 9, 12
(
(b)
(4)
(b) (4) (b) (4)month ) time intervals, but actually conducted all of these tests on the same day, or
within a period of days.”

For Fluconazole Tablets and Ciprofloxacin Tablets, we found that even after Ranbaxy
submitted its August 2006 warning letter response with the corrected stability test
dates, the firm continued to submit the false stability test dates in annual report
submissions to the respective applications.
These submissions of false information about

the stability testing of the products were
material to FDA’s review of the applications.

Sources:

http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/EnforcementActivitiesbyFDA/ucm118418.pdf

http://www.in-pharmatechnologist.com/Processing/Ranbaxy-inks-consent-decree-prepares-for-500m-penalty

http://features.blogs.fortune.cnn.com/2013/05/15/ranbaxy-fraud-lipitor/

Man Pays Cab Fare…With Marijuana!


A man in Philadelphia tried to pay the Cab Fare with Marijuana and was arrested.

 

Had he had not had prior experience, he would not attempted?

 

Story;

A Philadelphia man, short on cash, learned that lesson the hard way when he allegedly tried to pay his $8 cab fare with marijuana, according to local news outlets.

Sixth District Police Captain Brian Korn said 23-year-old Michael Medvec “tried to slip the cabbie a bag of marijuana to pay for the fare” Friday night on Chestnut Street in Old City, CBS Philadelphia reports.

Unfortunately for him, officers were standing within several feet of the cab and responded quickly when a driver reported that Medvec couldn’t pay what was owed.

“They can’t ignore it,” Korn said, explaining to Philly.com that the attempt was made in their presence. “You do something silly, you need to get spanked a little.”

Medvec was arrested and charged with possession of marijuana Friday and was released the next day.

http://www.huffingtonpost.com/2013/04/02/marijuana-cab-fare-michael-medvec_n_3001245.html?ir=Weird+News&ref=topbar

War On Drugs ,Coming To A close


The  Organised War on Drugs is about a hundred years old.

Look at the use of Drugs Statistics.

The Global picture

Globally, it is estimated that in 2010 between 153 million
and 300 million people aged 15-64 (3.4-6.6 per cent of
the world’s population in that age group) had used an illicit
substance at least once in the previous year. The extent of
illicit drug use has thus remained stable, but the estimated
15.5 million-38.6 million problem drug users (almost 12
per cent of illicit drug users), including those with drug
dependence and drug-use disorders, remain a particular
concern.
It is also estimated that there were between 99,000 and
253,000 deaths globally in 2010 as a result of illicit drug
use, with drug-related deaths accounting for between 0.5
and 1.3 per cent of all-cause mortality among those aged
15-64.
1
Moreover, it was estimated that in 2008 there were
16 million injecting drug users worldwide and that 3 million (18.9 per cent) of them were living with HIV, though
no new figures are available after 2008. Global prevalence
of hepatitis C infection among injecting drug users in 2010
was 46.7 per cent, meaning that some 7.4 million injecting drug users worldwide are infected with hepatitis C.
And some 2.3 million injecting drug users are infected
with hepatitis B. Evidence is also emerging that non-injecting drug use is also associated with an increased risk of
HIV infection, principally due to unprotected sex.”

With estimated annual prevalence of cannabis use in 2010
ranging from 2.6 to 5 per cent of the adult population
(between 119 million and 224 million estimated users aged
15-64), cannabis remains the world’s most widely used
illicit substance (see figure 1). There may be shifts in cannabis use between the drug’s two principal forms, resin and
herb, and there is even evidence of the increasing popularity of synthetic marijuana among young people in some
regions, but in general annual prevalence of cannabis use
remained stable in 2010…”

Money Spent on War On Drugs.

Nations, especially the US has been spending huge money on War on Drugs.

Federal Drug Control BudgetUS Dollars (In Millions)
- Year -  - Total -  Demand Reduction  % of - Total -  Supply Reduction  % of - Total -  Domestic Law Enforcement   International   Interdiction 
2004 19,188.4 8,579.0 44.7% 10,609.4 55.3% 7,051.7 2,008.7 1,549.0
2005 20,371.6 8,798.2 43.2% 11,573.4 56.8% 7,267.5 2,432.2 1,873.7
2006 21,133.1 8,775.2 41.5% 12,357.9 58.5% 7,538.9 2,923.2 1,895.8
2007 22,175.1 9,056.6 40.8% 13,118.5 59.2% 7,881.9 3,045.2 2,191.4
2008 22,497.1 9,244.9 41.1% 13,252.2 58.9% 8,286.7 2,967.0 1,998.5
2009 25,579.5 10,332.7 40.4% 15,246.8 59.6% 9,017.1 3,697.1 2,532.6
2010 25,887.1 10,443.2 40.3% 15,443.9 59.7% 9,190.9 3,658.0 2,595.0
2011 25,731.6 10,563.8 41.1% 15,167.8 58.9% 9,093.6 3,706.7 2,367.5
2012 26,209.6 10,664.8 40.7% 15,544.8 59.3% 9,505.4 3,901.0 2,138.4
TOTAL 208,773.1 86,458.4 41.4% 122,314.7 58.6% 74,833.7 28,339.1 19,141.9
% Chg/2004-2012 +36.6% +24.3% +46.5% +34.8% +94.2% +38.1%
For more Statistics and information on Drug abuse,pattern age group please refer  the links at the end of the Post.
Now some States have started legalizing marijuana, admmitting that the War on Drugs is not yielding results and more illicit Drug and more usage is reported.

The idea to scale down th War on Drugs is gaining ground.

The commission presented a 20-page report, the first sentence of which read: “The global war on drugs has failed, with devastating consequences for individuals and societies around the world.” Nadelmann wrote the sentence, as well as the report’s entire executive summary. He advised the commission, and he also searched for high-profile members.

One of the speakers at the press conference in the Waldorf Astoria was an amiable man with glasses: César Gaviria, the president of Colombia from 1990 to 1994. While in office, he did almost everything except fight a war. Colombia was what Mexico is today: a country hijacked by drug lords.

“An irrational and pointless drug policy was partly responsible for that period,” says Gaviria today.”

The war on Drugs intensified during the Nixon Era.

In 2010, about 200 million people took illegal drugs. The numbers have remained relatively constant for years, as has the estimated annual volume of drugs produced worldwide: 40,000 tons of marijuana, 800 tons of cocaine and 500 tons of heroin. What has increased, however, is the cost of this endless war.

In the early 1970s, the Nixon administration pumped about $100 million into drug control. Today, under President Barack Obama, that figure is $15 billion — more than 30 times as much when adjusted for inflation. There is even a rough estimate of the direct and indirect costs of the 40-plus years of the drug war: $1 trillion in the United States alone.

In Mexico, some 60,000 people have died in the drug war in the last six years. US prisons are full of marijuana smokers, the Taliban in Afghanistan still use drug money to pay for their weapons, and experts say China is the drug country of the future.

Taking into account the high cost of War OnDrugs and the results it has produced the thought is on legalising the Trade of Drugas.

When about 30 national leaders met in Cartagena, Colombia, in April 2012 for the Summit of the Americas, there was only big, behind-the-scenes topic: a new drug policy. Suddenly Colombian President Juan Manuel Santos was saying: “If the world decides to legalize (drugs) and thinks that that is how we reduce violence and crime, I could go along with that.”

General Otto Pérez Molina, president of Guatemala, wrote: “Consumption and production should be legalized but within certain limits and conditions.”

Uruguayan President José Mujica said: “What scares me is drug trafficking, not drugs”.

Vicente Fox, the president of Mexico from 2000 to 2006, wanted to wage the “mother of all wars” against organized crime, sending the Mexican army into the drug war. Today, Fox says that the war was a “total failure.”

In fact, sitting in Nadelmann’s office in Manhattan, it really is difficult to imagine a world without the drug war. A future in which marijuana and cocaine are legal and can be purchased in pharmacies or specialty drug shops? A life in which everyone decides for him- or herself: Am I going to take this drug? How much am I going to take? How do I protect my children?

It isn’t an easy thing to imagine. In fact, the very thought of it creates a gut-wrenching feeling, and it makes you ask yourself questions like: Legalizing drugs? Are you folks nuts?”

Sane Policy.

Gambling, Prostitution, Drinking and use of Intoxicants have been a part of Man since time immemorial.

Investing money on something to prohibit which a Man wants to do, is not a sound idea.

The best is to legalize it and provide adequate safeguards for individual’s health.

Despite this, if some one wants to poison himself to death, one can do nothing.

Jhon Velásquez, aka

Jhon Velásquez, aka “Popeye,” was a brutal killer as head of security for Pablo Escobar, head of Colombia’s Medellín cartel until his death in 1993

A man works in a coca lab in Putumayo: None of the materials or equipment needed to produce cocaine are expensive, sophisticated or hard to obtain. The end product is cocaine hydrochloride, or pure cocaine. A good laboratory with a well-trained team can produce 500 kilograms (1,100 lbs.) a day

A man works in a coca lab in Putumayo: None of the materials or equipment needed to produce cocaine are expensive, sophisticated or hard to obtain. The end product is cocaine hydrochloride, or pure cocaine. A good laboratory with a well-trained team can produce 500 kilograms (1,100 lbs.) a day

http://www.spiegel.de/international/world/global-support-grows-for-legalizing-drugs-a-884750-4.html

Stop The Abuse Of Drugs ,Look At This.


Time and diseases ravage one.

These can not be controlled by any one.

Despite information to the contrary, people abuse drugs, knowing fully well what it can do to their Heath.

I do not mean only the use of hard drugs.

This applies high use of Steroids,over consumption of Antibiotics as well.

Even if you do not care about your Health,(deterioration is not visible), please look these Photos, and stop misusing Drugs.

Hope you are conceited enough about your looks at least.

Drug Abuse 1_jpg.

The photographer captured subjects in the studio using make-up and combined the before and after images to make these powerful photos

Drug Abuse_jpg.

Drug Abuse.

Drug Abuse_jpg.

Two sides to every story: The photographer’s eye-catching images prompts people to think about the history behind drug abuse

Many would automatically assume judgements about those caught in the grip of drug addiction.

But one photographer has sought to overcome the stereotypes by presenting both faces of a drug addict – the classic before and after picture.

Using make up and models, Roman Sakovich showed one half of a face ravaged by drugs, including cut lips, scabbed skin, matted hair.

But he also peeled back the years to show the person before their descent into addiction, showing them in smart clothes with neat hair.

These startling photos, posed by subjects, are part of Mr Sakovitch’s ‘Half’ project, which he created with make up ‘in order to explore the outsiders superficial judgement of the same person before and after drug abuse’, according to Features Shoot .

 

http://www.dailymail.co.uk/news/article-2232632/The-sides-drug-abuse-The-startling-photos-ravaging-effects-substance-addiction.html

 

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Mind Control Drug That Robs off Free Will? Video


Scopolamine, otherwise known as “The Devil’s Breath,” was tested by the CIA as a truth serum during the Cold War, and it was also reportedly used by Nazi interrogators during World War II, was /is being used in Relaxation Technic for Stress and other Related Disorders.

It is also used as Test Serum.

Many Thriller writers use this in their Novels.

Alistair McLean describes its effects in his Book The last Frontiers.

CIA is known to use this quite frequently at the time of Debriefing its own Agents , Assets and Double Agents.

Now the real danger of the Drug is being revealed now.

Story.

Scopolamine, otherwise known as “The Devil’s Breath,” was tested by the CIA as a truth serum during the Cold War, and it was also reportedly used by Nazi interrogators during World War II, he added.

Likewise, Beth Stebner of the Daily Mail said that “stories surrounding the drug are the stuff of urban legends, with some telling horror stories of how people were raped, forced to empty their bank accounts, and even coerced into giving up an organ.”

VICE correspondent Ryan Duffy interviewed a drug dealer operating out of the Columbian capital of Bogota, who told him that the drug was, in Stebner’s words, “frightening for the simplicity in which it can be administered” and prevents a person from remembering anything that happened to them while under the influence.

Duffy himself described his experiences as it relates to the drug on the VICE website.

“When VICE initially asked me to go down to Colombia to dig into this Scopolamine story… I had only a vague understanding of the drug, but the idea of a substance that renders a person incapable of exercising free-will seemed liked a recipe for hilarity and the YouTube hall of fame. I even spent a little time brainstorming the various ways I could transport some of it back to the states and had a pretty good list going of different ways to utilize it on my buddies,” he said.

“The original plan was for me to sample the drug myself to really get an idea of the effect it had on folks,” Duffy said. “The producer and camera man had flew down to Bogota ahead of me to confirm some meetings and start laying down the groundwork. By the time I arrived a few days later, things had changed dramatically. Their first few days in the country had apparently been such a harrowing montage of freaked-out dealers and unimaginable horror stories about Scopolamine that we decided I was absolutely not going to be doing the drug. All elements of humor and novelty were rapidly stripped away during my first few days in town. After meeting only a couple people with firsthand experience, the story took a far darker turn than we ever could have imagined.”
redOrbit (http://s.tt/1bDbQ)