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Posts Tagged ‘Doctor of Philosophy’

How Body Cells Kill Cancer Cells Video

In Health on August 20, 2012 at 19:07

 

In this video we see a killer T cell of the immune system attacking a cancer cell.

Professor Gillian Griffiths:
“Cells of the immune system protect the body against pathogens. If cells in our bodies are infected by viruses, or become cancerous, then killer cells of the immune system identify and destroy the affected cells. Cytotoxic T cells are very precise and efficient killers. They are able to destroy infected or cancerous cells, without destroying healthy cells surrounding them. The Wellcome Trust funded laboratory of Professor Gillian Griffiths, at the Cambridge Institute for Medical Research, investigates just how this is accomplished. By understanding how this works, we can develop ways to control killer cells. This will allow us to find ways to improve cancer therapies, and ameliorate autoimmune diseases caused when killer cells run amok and attack healthy cells in our bodies.”

Cytotoxic T cells are just 10 microns in length: approximately one-tenth the width of a human hair. These movies are 92 times real time.

The original footage shown was made by Alex Ritter, a PhD student on the NIH-OxCam programme, in the laboratory of Professor Gillian Griffiths at the Cambridge Institute for Medical Research and the Department of Medicine of the Clinical School of the University of Cambridge. The images were acquired using an Andor Revolution spinning disk system with an Olympus microscope. Professor Griffiths is a Wellcome Trust Principal Research Fellow.

Links:

www.cimr.cam.ac.uk

www.cimr.cam.ac.uk/investigators/griffiths/index.html

www.immunology.cam.ac.uk/about

 

Heart Disease in Women.

In Hindi Blogs on January 26, 2011 at 09:04

Signs of heart disease in women.

The most important sign is feeling really tired–even if after enough sleep. Other signs of heart disease in women are:

  • Trouble breathing
  • Trouble sleeping
  • Feeling sick to the stomach
  • Feeling scared or nervous
  • New or worse headaches
  • An ache in the chest
  • Feeling “heavy” or “tight” in the chest
  • A burning feeling in the chest
  • Pain in the back, between the shoulders
  • Pain or tightness in the chest that spreads to the jaw, neck, shoulders, ear, or the inside of the arms
  • Pain in the belly, above the belly button

There is good news: You can take steps to keep your heart healthy.

Don’t wait to get help!

Go to your doctor or clinic if you have any warning signs.

Lower Your Risk of Heart Disease

  • Find out if heart disease runs in your family.
  • Visit your doctor or clinic often. Find out if you are at risk.
  • Don’t smoke. Stay away from other people who are smoking.
  • Get your blood pressure checked often. You might need medicine to keep it at the right level.
  • Control your diabetes.
  • Get your cholesterol checked often.
  • Stay active. Walking every day can lower your chances of a heart attack.
  • Eat right and keep a healthy weight.
  • Eat less salt.
  • If you take birth control pills, don’t smoke.
  • Hormones for menopause should not be used to prevent heart attacks.
  • Being stressed, angry or sad a lot may add to your risk of heart attack.
  • If you’ve had a heart attack, talk to your doctor about medicine. Some medicines can help cut down the risk of having another heart attack.

High Blood Pressure

  • High blood pressure adds to the chance of having heart disease.
  • High blood pressure is called the “silent killer”. Most people who have it do not feel sick and don’t know that they have it.
  • Have your blood pressure checked each time you go to the doctor or clinic.

To learn more:http://www.fda.gov/ForConsumers/ByAudience/ForWomen/ucm118528.htm

Related:

Middle-aged women who take steps to lower their blood pressure could reduce their risk of having a stroke, heart attack, or developing heart failure, a new study shows.

Researchers say they found that high systolic pressure — the blood pressure when the heart contracts — is a significant risk factor for cardiovascular disease and its complications in middle-aged and older women.

Doctors say 36% of serious cardiovascular events such as heart attacks and strokes are preventable by lowering blood pressure in women, compared to only 24% in men.

For the study, investigators examined data on 9,357 adults in 11 countries in Europe, Asia, and South America for a median of 11 years. The researchers looked for absolute and relative risks of cardiovascular disease that were associated with systolic blood pressure.

They report that three major risk factors account for 85% of the modifiable risk for heart disease in men and women — high systolic (the top number) blood pressure, high cholesterol, and smoking. And high systolic pressure is the most important risk factor, according to the researchers.

Prevention of Heart Disease

“I was surprised by the study findings that highlight the missed opportunities for prevention of heart disease in older women,” researcher Jan A. Staessen, MD, PhD, of the University of Leuven in Belgium, says in a news release.

He says the research team found that a relatively small increase of 15 points in systolic blood pressure increased the risk of cardiovascular disease by 56% in women and 32% in men.

For the study, the researchers looked at ambulatory blood pressure, which involves measuring blood pressure at set intervals for 24 hours during a person’s daily routine and when asleep, and conventional blood pressure readings taken in doctors’ offices.

The researchers say ambulatory blood pressure readings have less potential for error and provide more accurate estimates of usual blood pressure and prognosis for cardiovascular disease.

The monitor used for ambulatory readings was a small, portable device programmed to take blood pressures at specific intervals. In the study, ambulatory readings were taken at intervals of 15 to 30 minutes during the daytime, and 30 to 45 minutes at night.

Nighttime readings are a better predictor of heart disease than daytime readings because the readings taken at night are more standardized, the researchers say. And blood pressure at night is less likely to be influenced by physical activity.

Quality of Life

“It is recognized that women live longer than men, but that older women usually report lower quality of life than men,” Staessen says. “By lowering systolic pressure by 15 [points] in hypertensive women, there would be an increased benefit in quality of life by prevention of cardiovascular disease.”

The researchers say that women and their doctors ought to become more aggressive in diagnosing and treating high systolic blood pressure.

The study is published in Hypertension: Journal of the American Heart Association

http://www.webmd.com/hypertension-high-blood-pressure/news/20110124/heart-benefits-for-women-who-cut-hypertension?src=RSS_PUBLIC

Link between light and Body clock

In Health on December 30, 2010 at 09:17

Diagram illustrating the influence of dark-lig...

Image via Wikipedia

 


 

 

 

 

For a detailed understanding on this please read my blog on Time ( under Time),Brain’s Architecture(health).

In a new paper published this week in the Proceedings of the National Academy of Sciences, Aziz Sancar, MD, PhD, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, and his colleagues have taken an important step in understanding the underlying molecular signals that influence a broad array of biological processes ranging from the sleep-wake cycle to cancer growth and development.

http://www.physorg.com/news/2010-12-scientists-link-circadian-rhythms.html

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